Department of Cell Biology
The movies on this page were created from data collected during an analysis of a fusion of the Ncd microtubule motor protein to the green fluorescent protein (GFP) of the jellyfish, A. victoria. The analysis was carried out in live Drososphila embryos to determine the effects of the Ncd-GFP motor on mitotic spindle dynamics. Results of this analysis have been published in the October 1996 issue of the Journal of Cell Science. The movies below correspond to data presented in the indicated figure of the manuscript. Click on the icon to download and view each movie (except Fig. 5 which plays on the page). View the legends.
Fig. 1. Mitotic spindles visualized with Ncd-GFP in a cleavage stage Drosophila embryo.
Fig. 2. Ncd-GFP distribution in metaphase spindles differs from that of tubulin.
Fig. 3. Spindle fibers associated with Ncd-GFP extend across the chromosomes in metaphase.
Fig. 4. Embryos mutant for ncd-gfp* show spindle abnormalities in mitosis.
Fig. 5. Chromosome mis-segregation and loss in an ncd-gfp* mutant embryo.
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