I am motivated by questions aimed at understanding how cis-regulatory element evolution impacts organismal phenotypes, how developmental mechanisms evolve, and how comparative evolutionary genomics can inform our understanding of the genotype to phenotype map. Specifically, I am using comparative high-throughput sequencing approaches to understanding how differences in transcription and regulation lead to differences in phenotypes.

 

Chimapanzee image from: http://commons.wikimedia.org/wiki/File:Chimpanzee-Head.jpg

Human image from Rembrandt van Rijn