"What you can not create, you can not understand.", Richard Feynman

Highlights

    Published 12 papers in multi-disciplinary research areas, which include optimization algorithms, biophysics, modeling of biological pathways, and synthetic biology.
    Possessed seven years research experience in both computational and experimental biology.
    Collaborated effectively and productively with cancer biologist, biochemist, engineers, and statisticians.

Peer Reviewed

(Cumulative cites: 142)
  1. G. Yao, C. Tan, L. You, and J. Nevins. Essential regulations of bistable mammalian cell cycle entry, In preparation, 2009.

  2. C. Tan and L. You. Dynamical signatures of circuit-host-environment interactions, In preparation, 2009.

  3. C. Tan, P. Marguet, and L. You. Emergent bistability by a growth-modulating positive feedback circuit. Nature Chemical Biology, In press, 2009.

  4. Q. Wang, J. Niemi, C. Tan , L. You and M. West. Image segmentation and dynamic lineage analysis in single-cell fluorescent microscopy. Journal of Synthetic Biology, In press, 2009.

  5. C. Tan, F. Reza, and L. You. Noise-limited frequency signal transmission in gene circuits. Biophysical Journal, 2007. pdf

  6. C. Tan, H. Song, J. Niemi, and L. You. A synthetic biology challenge: making cells compute. Molecular BioSystems, 2007. pdf

  7. P. Marguet, F. Balagadde, C. Tan, and L. You. Biology by design: reduction and synthesis of cellular components and behaviour. J. Royal Society Interface, 2007. pdf

  8. K.-H. Chiam*, C. Tan*, V. Bhargava, and G. Rajagopal. Hybrid simulations of stochastic reaction-diffusion processes for modeling intracellular signaling pathways. Physical Review E, 2006 (*Equal contribution). pdf

  9. P. Dhar, C. Tan, S. Somani, Y. Li, K. Sakharkar, A. Krishnan, A. Ridwan, M. Chitre, and H. Zhu. Grid Cellware: The first Grid-enabled tool for modeling and simulating cellular processes. Bioinformatics, 2005, Vol 21, Number 7, pp 1284-1287. pdf

  10. C. Tan, S. Somani, and P. Dhar. Modeling and simulation of biological systems with stochasticity. In-Silico Biology, 4, 0024, 2004. pdf

  11. P. Dhar, C. Tan, S. Somani, Y. Li, A. Sairam, M. Chitre , H. Zhu, and K. Sakharkar. Cellware: a multi-algorithmic software for computational systems biology. Bioinformatics, 2004, Vol 20, Number 8, pp 1319-1321. pdf

Conference Papers

  1. T. Ray, H. Tsai, and C. Tan. Effects of Solver Fidelity on a Parallel Search Algorithm's Performance for Airfoil Shape Optimization Problems. 9th AIAA/ISSMO Symposium on Multidisciplinary Analysis and Optimization Conference, 2002, Atlanta, Georgia. pdf

  2. C. Tan, T. Ray, and H. Tsai.Effects of Adaptive Search Space Operator on Performance of SWARM Algorithm for Airfoil Design Optimization. 41st Aerospace Sciences Meeting and Exhibit, 2003, Reno, Nevada.

  3. C. Tan, T. Ray, and H. Tsai. A Comparative Analysis of Evolutionary Algorithm and Swarm Algorithm for Airfoil Design Problems. 41st Aerospace Sciences Meeting and Exhibit, 2003, Reno, Nevada.

Book Chapters

  1. H. Song, S. Payne, C. Tan, and L. You. Engineering bacterial cell-cell communication. N. Bergman (Editor). Wiley-Blackwell. Submitted, 2008.

  2. T. Lee, C. Tan, D. Tu, and L. You. Modeling cellular networks. In Bioinformatics: An Engineering Case-Based Approach, Eds. G. Alterovitz & M. Ramoni. In press, 2007

Presentation

  1. Growth modulation turns a noncooperative positive feedback bistable. Institute of Biological Engineering Annual Meeting, Chapel Hill, 2008.

  2. Bistability in an integrated protein and gene regulatory network. Biomedical Engineering Society Annual Fall Meeting 2006, Chicago