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My Research
I am broadly interested in the causes and consequences of recombination rate variation in Drosophila. Specifically, I am working to:
- Both statistically and empirically look for interspecies recombination between inversions that are fixed between D. pseudoobscura and D. persimilis.
Inversions are thought to maintain species by preventing between species recombination. I am interested in the extent of this recombination reduction.
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- Examine patterns of recombination rate variation in Drosophila persimilis using a fine-scale mapping approach.
I am working to generate a genome-wide portrait of recombination rate across the D. persimilis genome using high-throughput sequencing and genotyping technologies. I am currently looking at how recombination rate varies within the genome and with genetic factors such as genetic diversity, divergence and various sequence motifs, etc.
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- Test for potentially male-mediated effects on recombination rate in Drosophila melanogaster.
For this project, I hypothesize that males have the ability to alter their proportion of recombinant progeny by influencing recombination rates in females and this trait varies among males as a result of standing genetic variation and/or male rearing environment.
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